Polynucleotide Injections in Brașov
Discover the polynucleotide injection service at ArtMedica Brașov. This is an innovative solution for deep skin regeneration, wrinkle reduction, and regaining a radiant and healthy complexion.

What is polynucleotide injection?
Polynucleotide injection is an advanced skin biorevitalization procedure, using DNA fragments typically extracted from salmon genetic material. These polynucleotides, key components of DNA, play an important role in tissue regeneration and repair. Studies have shown that the use of polynucleotides in aesthetic medicine can improve skin texture, reduce wrinkle depth, and improve the overall appearance of the face.
At ArtMedica Clinic in Brașov, we use the PhilArt product by Croma, recognized for its effectiveness in stimulating collagen and elastin production. This treatment not only deeply hydrates the skin, but also improves its elasticity and firmness, resulting in a rejuvenated and healthy appearance.
What are the benefits of polynucleotide injection?
Polynucleotide injection is a safe and effective solution for skin revitalization, with notable effects in facial rejuvenation. Among its benefits are:
- Stimulating cellular regeneration: polynucleotides activate fibroblasts, promoting the natural synthesis of collagen and elastin. The skin becomes firmer, denser, and more luminous.
- Deep hydration and antioxidant effect: the molecules attract water into the dermis and protect cells from oxidative stress, providing a fresh and healthy appearance.
- Reducing fine wrinkles and expression lines: especially in delicate areas such as the eye contour and upper cheeks.
- Improving the appearance of dark circles: polynucleotide treatment helps reduce mild pigmentation and diminish the “thin skin” look around the eyes, providing a more rested and younger appearance.
- Re-densification of the under-eye skin: by stimulating tissue regeneration, the skin in the dark circle area becomes thicker and firmer, reducing the vascular transparency that accentuates shadows.
- Excellent tolerance in sensitive areas: this is one of the few injectable therapies that can be used successfully and safely in the periocular region.
These benefits make polynucleotide therapy a valuable ally in natural rejuvenation, without artificial effects or excess volume.

How is the polynucleotide injection procedure performed at ArtMedica Clinic?

- Initial consultation: The procedure begins with an evaluation by the specialist doctor, who analyzes the patient’s skin condition, aesthetic goals, and any contraindications. Based on this information, a personalized treatment plan is established.
- Skin preparation: The area to be treated is carefully cleansed and disinfected, and a local anesthetic cream is applied for patient comfort. This way, the procedure is carried out with minimal discomfort.
- Polynucleotide injection: The product is gently injected into the skin, in areas such as the face, eye contour, neck, décolletage, or hands. The substance works at a deep level, stimulating cellular regeneration and restoring the skin’s firmness, elasticity, and natural luminosity.
- Treatment completion: After the procedure, a soothing cream is applied. In some cases, slight redness or swelling may appear in the injected areas, which can last from a few hours to 1-2 days. These reactions are normal and temporary.
- Recommended protocol: For optimal results, a protocol of 3 to 4 sessions is recommended, performed at intervals of 2-3 weeks. Afterwards, maintenance sessions can be performed every 2-3 months, depending on the skin’s progress and the patient’s goals.
Frequently Asked Questions about Polynucleotide Injection
Who is polynucleotide treatment for?
The treatment is suitable both for younger people who want to prevent signs of aging, and for mature patients who want to improve the elasticity, texture, and firmness of their skin. It is recommended especially for those looking for a natural alternative to volumizing or invasive procedures and who want a rejuvenated but discreet look. It is also ideal for sensitive areas, such as the eye contour, where other treatments may be too aggressive.
How safe is the procedure and what side effects may occur?
Polynucleotide injection is a safe procedure, well tolerated by most patients. Mild reactions such as redness, swelling, or small bruises in the injected area may occur, which usually disappear within a few hours to 1-2 days. Due to its biocompatible composition, the risk of adverse reactions is extremely low.
When do results become visible and how long do the treatment effects last?
The first improvements in skin texture and luminosity can be noticed as early as 2-4 weeks after the first session. Optimal results appear after completing the full protocol (3-4 sessions) and can be maintained for 6-12 months, depending on lifestyle, age, and skin quality. Maintenance treatments every few months are recommended.
Are there contraindications for this treatment?
Yes. The treatment is not recommended for people with active skin infections, autoimmune diseases, coagulation disorders, known allergies to the product components, pregnant women, or breastfeeding women. It is important for the patient to discuss their medical history with the doctor before the procedure.
Can polynucleotide treatment be combined with other aesthetic procedures?
Yes, polynucleotides can be successfully combined with other treatments such as botulinum toxin, hyaluronic acid, laser therapies, microneedling, or radiofrequency. They can also be used as a preparatory treatment before more intense procedures, to improve the overall result and skin quality.














